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Mattress and Pillow Encasings References

Dust-free bedrooms in the treatment of asthmatic children with house dust or house dust mite allergy: a controlled trial.

AUTHORS: Murray AB; Ferguson AC
SOURCE: Pediatrics 1983 Mar; 71(3): 418-22
CITATION IDS: PMID: 6338475 UI: 83143089
ABSTRACT: Twenty asthmatic children with prick tests positive for house dust or house dust mites were allocated to two groups that were matched for severity. One group was provided with zippered vinyl covers for pillows, mattresses, and box springs, and instructions for making the bedroom as easy to keep clean as a hospital ward; the other group was not. At the end of a 1-month study period, there was a marked and statistically significant difference in symptoms and signs of asthma between the two groups. Those with a dust-free bedroom had fewer days on which wheezing was observed, medication was given, or an abnormally low peak expiratory flow rate was recorded. Bronchial tolerance to aerosolized histamine significantly improved in the group whose bedrooms had been modified. A dust-free bedroom diminishes bronchial irritability and is a practical and effective method for decreasing asthma in children with house dust or house dust mite allergy.


Allergen avoidance in house dust mite sensitive adult asthma.

AUTHORS: Walshaw MJ; Evans CC
SOURCE: Q J Med 1986 Feb; 58(226): 199-215
CITATION IDS: PMID: 3520626 UI: 86233964
ABSTRACT: Fifty adult asthmatic patients with strongly positive skin prick tests to the house dust mite were admitted into a prospective randomised controlled trial of house dust mite avoidance in the community. Twenty- two of the experimental group completed one year of dust avoidance and 19 of these tolerated the use of plastic mattress and pillow covers. Twenty of the control group (who did not alter their housecleaning habits) also completed one year of study. A fall in mite and dust levels was noted in the homes of the experimental but not the control group. Fifteen of the experimental group who completed the study were strongly RAST positive (score 3 or more) to the house dust mite. These patients had a significant improvement in FEV1/FVC, PEFR, PC20, use of treatment, and symptom score at one year, whilst the seven experimental patients who were not strongly RAST positive (score 2 or less) did not, suggesting that the change noted in the former patients was not merely due to a placebo effect. Fifteen of the control group who completed the study were also strongly RAST positive for the house dust mite and these patients showed no change in any of the parameters. This study demonstrates that adult asthmatic patients can successfully carry out house dust eradication procedures in the community over a long period of time, and that those patients who are allergic to the house dust mite appear to have both subjective and objective improvement in their asthma.


The Melbourne house dust mite study: eliminating house dust mites in the domestic environment.

AUTHORS: Hill DJ; Thompson PJ; Stewart GA; Carlin JB; Nolan TM; Kemp AS; Hosking CS
AUTHOR AFFILIATION: Department of Allergy, Royal Children's Hospital, Parkville, Australia.
SOURCE: J Allergy Clin Immunol 1997 Mar;99(3):323-9
CITATION IDS: PMID: 9058687 UI: 97211720

BACKGROUND: Hypersensitivity to house dust mite allergens is associated with increased asthma morbidity. Asthma severity appears to be related to the degree of mite allergen exposure. Short-term studies suggest that complete avoidance reduces disease severity.
OBJECTIVE: The study was designed to assess the effect of different mattress covers and floor coverings on mite allergen concentrations in the homes of mite- sensitive children with asthma in the city of Melbourne, Australia.
METHODS: Mite allergen Der p 1 concentration was measured on mattress covers, mattress surfaces, and carpeted and uncarpeted floors in 107 dwellings; and measurement was performed on three occasions over a 5- month period. After the first sampling, all mattress covers and impermeable encasements were permanently removed.
RESULTS: The initial geometric mean concentrations of Der p 1 (micrograms per gram of fine dust) from the surfaces of sheepskin, wool, and cotton mattress coverings were greater than those from the surfaces of impermeable mattress encasements (116, 113, and 19 vs 0.4) (p < 0.001); corresponding concentrations on the underlying mattresses were 142, 38, 20, and 0.6, respectively (p < 0.05 to 0.001). At the end of the study these mattress surface concentrations were 79, 65, 9.7, and 3.1, respectively. In 24 dwellings an uncarpeted room was adjacent to a carpeted room. At each visit the concentration of Der p 1 in uncarpeted rooms was below the reported threshold for sensitization and significantly less than that in the adjacent carpeted room.
CONCLUSION: In homes of children with asthma, "asthmogenic" concentrations of Der p 1 were found on nonencased mattresses and carpeted floors, but the use of impermeable mattress encasements and carpet exclusion were associated with concentrations of Der p 1 below the reported threshold for sensitization.


Evaluation of materials used for bedding encasement: effect of pore size in blocking cat and dust mite allergen.

AUTHORS: Vaughan JW; McLaughlin TE; Perzanowski MS; Platts-Mills TA
AUTHOR AFFILIATION: University of Virginia Asthma and Allergic Diseases Center, Charlottesville 22908, USA.
SOURCE: J Allergy Clin Immunol 1999 Feb; 103(2 Pt 1): 227-31
CITATION IDS: PMID: 9949312 UI: 99135988

BACKGROUND: Mattress and pillow encasings are recommended for patients allergic to dust mites. Many encasements block allergen and are vapor permeable but do not allow free passage of air through the material. Recently, breathable fabrics made from tightly woven synthetic fibers or nonwoven synthetics have been recommend as encasements. OBJECTIVE: The purpose of this study was to develop a method for testing encasement materials made of breathable fabrics. METHODS: Dust samples containing a known quantity of allergen (Der f 1, Der p 1, and Fel d 1) were pulled across a variety of fabrics using a modified dust trap. Airflow through the dust trap was controlled with a vacuum pump. Five minutes after dust was introduced, the pump was shut off. A filter located downstream of the fabric collected allergen passing through the fabric during the test and was assayed with ELISA for the relevant allergen. Fabrics to be tested were obtained from manufacturers and specialty catalogs. RESULTS: As the average pore size decreases, the airflow through a fabric becomes restricted, and the pressure differential created by the vacuum pump increases. Dust mite allergens (Der f 1 and Der p 1) were blocked below detectable limits by fabrics of less than 10 microm in pore size. Fabrics with an average pore size of 6 microm or less blocked cat allergen (Fel d 1). CONCLUSION: The method we developed provided a rigorous and reliable test for leakage of common indoor allergens through breathable barrier fabrics. Our results show that tightly woven fabrics and nonwoven synthetic fabrics can block common indoor allergens but still allow airflow.